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  2. Ranitidine - Wikipedia

    en.wikipedia.org/wiki/Ranitidine

    Ranitidine was introduced in 1981, and was the world's biggest-selling prescription drug by 1987. [132] Subsequently, it was largely superseded by the more effective proton-pump inhibitor (PPI) class of drugs, with omeprazole becoming the biggest-selling drug for many years.

  3. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    Proton-pump inhibitors have largely superseded the H 2-receptor antagonists, a group of medications with similar effects but a different mode of action, and heavy use of antacids. [3] A potassium-competitive acid blocker (PCAB) revaprazan was marketed in Korea as an alternative to a PPI.

  4. Zantac - Wikipedia

    en.wikipedia.org/wiki/Zantac

    Zantac can refer to either of two different H 2 antagonists used to reduce gastric acid secretion: Ranitidine, prior to its 2020 withdrawal from the market;

  5. H2 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H2_receptor_antagonist

    Ranitidine was introduced in 1981 and was the world's biggest-selling prescription drug by 1988. The H 2 receptor antagonists have since largely been superseded by the even more effective proton pump inhibitors (PPIs), with omeprazole becoming the biggest-selling drug for many years.

  6. GSK asks to appeal Delaware ruling allowing Zantac cases to ...

    www.aol.com/news/latest-trial-over-zantac-cancer...

    Some tests showed that Zantac's active ingredient, ranitidine, could degrade into NDMA over time or when exposed to heat. The U.S. Food and Drug Administration asked manufacturers to pull the drug ...

  7. The Best Alternatives to Zantac, Which the FDA Just ... - AOL

    www.aol.com/news/best-alternatives-zantac-fda...

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  8. GSK whistleblower claims drugmaker cheated US government over ...

    www.aol.com/news/gsk-faces-whistleblower-lawsuit...

    The New Haven-based lab said its testing in 2019 revealed that Zantac, also known as ranitidine, could form a cancer-causing carcinogen known as NMDA and was therefore "unfit for human consumption."

  9. Drugs for acid-related disorders - Wikipedia

    en.wikipedia.org/wiki/Drugs_for_acid-related...

    The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.

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