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As defined, acute inflammation is an immunovascular response to inflammatory stimuli, which can include infection or trauma. [24] [25] This means acute inflammation can be broadly divided into a vascular phase that occurs first, followed by a cellular phase involving immune cells (more specifically myeloid granulocytes in the acute setting). [24]
The terms acute-phase protein and acute-phase reactant (APR) are often used synonymously, although some APRs are (strictly speaking) polypeptides rather than proteins. In response to injury , local inflammatory cells ( neutrophil granulocytes and macrophages ) secrete a number of cytokines into the bloodstream, most notable of which are the ...
Periapical periodontitis or apical periodontitis [9] (AP) is an acute or chronic inflammatory lesion around the apex of a tooth root, most commonly caused by bacterial invasion of the pulp of the tooth. [10]
“For acute inflammation, you want to treat the underlying infection or injury,” says Dr. Dolansky. “Chronic inflammation requires treatment of the underlying chronic medical conditions.”
As with any form of inflammation, phlegmon presents with inflammatory signs dolor (localized pain), calor (increase local tissue temperature), rubor (skin redness/hyperemia), tumor (either clear or non-clear bordered tissue swelling), functio laesa (diminish affected function). There may be systemic signs of infection, such as fever, general ...
Once a DAMP is released from the cell, it promotes a noninfectious inflammatory response by binding to a pattern recognition receptor (PRR). [4] Inflammation is a key aspect of the innate immune response; it is used to help mitigate future damage to the organism by removing harmful invaders from the affected area and start the healing process. [5]
An acute exacerbation of a chronic condition. It is applied to a variety of conditions, including liver failure, [4] [5] subdural hematoma, [6] renal failure [7] respiratory failure, [8] [9] and bronchitis. Acute on chronic inflammation: A term sometimes used in pathology to describe a pattern of inflammation which is a mixture of chronic and ...
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