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Ketosis is a metabolic state characterized by elevated levels of ketone bodies in the blood or urine. Physiological ketosis is a normal response to low glucose availability. . In physiological ketosis, ketones in the blood are elevated above baseline levels, but the body's acid–base homeostasis is maintain
This state can be either physiologic or pathologic; physiologic ketotic hypoglycemia is a common cause of hypoglycemia in children, often in response to stressors such as infection or fasting. [1] Pathologic ketotic hypoglycemia is typically caused by metabolic defects, such as glycogen storage disorders. [2]
Ketone bodies are water-soluble molecules or compounds that contain the ketone groups produced from fatty acids by the liver (ketogenesis). [1] [2] Ketone bodies are readily transported into tissues outside the liver, where they are converted into acetyl-CoA (acetyl-Coenzyme A) – which then enters the citric acid cycle (Krebs cycle) and is oxidized for energy.
Starvation is a rare cause of ketoacidosis, usually instead causing physiologic ketosis without ketoacidosis. [5] Ketoacidosis from starvation most commonly occurs in the setting of an additional metabolic stressor such as pregnancy, lactation, or acute illness. [5] [6]
More than 38 million Americans have diabetes, and between 90% and 95% of them have type 2 diabetes. While most are adults over the age of 45, an increasing number of children and teens are also ...
As a result, trekking beyond the Earth's confines causes many physiological changes that affect an astronaut's health. Here is an explanation of some of the effects on human health caused by space ...
Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. [1] Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion and occasionally loss of consciousness. [1]
Less than three years before Elon Musk tapped him to help overhaul the US government, Edward Coristine, then 17, was the subject of a heated dispute among executives at cybersecurity firm over his ...