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Sildenafil’s ability to increase blood flow makes the medication useful for managing other conditions. Some sources suggest Viagra might make you last longer in bed, and others say it’s good ...
Research has found that taking Viagra does not increase high blood pressure. Sildenafil, the active ingredient in Viagra, is actually used to treat a certain kind of high blood pressure in the lungs.
Viagra and its main ingredient, sildenafil are medications known as PDE5 inhibitors. These drugs work to increase blood flow necessary for arousal when you're stimulated.
Sildenafil acts by blocking phosphodiesterase 5 (PDE 5), an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. [8] It requires sexual arousal to work, and does not by itself cause or increase sexual arousal. [8] It also results in dilation of the blood vessels in the lungs. [8]
Viagra (or sildenafil) lasts three to five hours after it’s consumed. Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
For example, in clinical trials of sildenafil, 28 percent of men reported headache (by far the most common side effect) at a dosage of 100mg, compared to just 16 percent of men who used 25mg and ...
The active ingredient in Viagra, sildenafil provides relief from ED for around four hours per dose. Tadalafil . The active ingredient in Cialis, tadalafil is a long-lasting medication that can ...
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