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A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings, cuts and burns. They often contain nerves and blood vessels.
Granulation tissue is composed of tissue matrix supporting a variety of cell types, [3] most of which can be associated with one of the following functions: formation of extracellular matrix; operation of the immune system; vascularisation; An excess of granulation tissue (caro luxurians) is informally referred to as "proud flesh". [4]
Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
Fibrosis can be used to describe the pathological state of excess deposition of fibrous tissue, as well as the process of connective tissue deposition in healing. [3] Defined by the pathological accumulation of extracellular matrix (ECM) proteins, fibrosis results in scarring and thickening of the affected tissue — it is in essence a natural ...
Appropriate treatment of a keloid scar is age-dependent: radiotherapy, anti-metabolites and corticosteroids would not be recommended to be used in children, in order to avoid harmful side effects, like growth abnormalities. [14] In adults, corticosteroids combined with 5-FU and PDL in a triple therapy, enhance results and diminish side effects ...
In medicine, desmoplasia is the growth of fibrous connective tissue. [1] It is also called a desmoplastic reaction to emphasize that it is secondary to an insult. Desmoplasia may occur around a neoplasm, causing dense fibrosis around the tumor, [1] or scar tissue within the abdomen after abdominal surgery. [1]
It aims to break up adhesions (scar tissue) on and around spinal joints as the cervical, thoracic, lumbar, sacral, and pelvic regions, or extremity joints as the knee, shoulder and hip, to which a restricted range of motion can be painful and limit function. Failed attempts at other standard conservative treatment methods (i.e., manipulation ...
Scar tissue is composed of the same protein as the tissue that it replaces, but the fiber composition of the protein is different; instead of a random basketweave formation of the collagen fibers found in normal tissue, in fibrosis the collagen cross-links and forms a pronounced alignment in a single direction. [1]