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Paracetamol, [a] or acetaminophen, [b] is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. [13] [14] [15] It is a widely available over-the-counter drug sold under various brand names, including Tylenol and Panadol.
4-Aminophenol is a building block used in organic chemistry. Prominently, it is the final intermediate in the industrial synthesis of paracetamol. Treating 4-aminophenol with acetic anhydride gives paracetamol: [8] [9] [10] It is a precursor to amodiaquine, mesalazine, AM404, parapropamol, B-86810 & B-87836 (c.f. WO 2001042204 ).
Phenacetin (/ f ɪ ˈ n æ s ɪ t ɪ n / ⓘ; acetophenetidin, N-(4-ethoxyphenyl)acetamide [1]) is a pain-relieving and fever-reducing drug, which was widely used following its introduction in 1887. It was withdrawn from medicinal use as dangerous from the 1970s (e.g., withdrawn in Canada in 1973, [ 2 ] and by the U.S. Food and Drug ...
The drug should be taken with acid food or drink (orange, apple or tomato juice). [9] PAS was once available in a combination formula with isoniazid called Pasinah [10] or Pycamisan 33. [11] 4-Aminosalicylic acid was approved for medical use in the United States in June 1994, and for medical use in the European Union in April 2014. [12] [1]
AM404, also known as N-arachidonoylphenolamine, [1] [2] is an active metabolite of paracetamol (acetaminophen), responsible for all or part of its analgesic action [3] and anticonvulsant effects. [4] Chemically, it is the amide formed from 4-aminophenol and arachidonic acid. AM404 is one of the AM cannabinoids discovered by Alexandros ...
The three aminophenol isomers: Left: 2-Aminophenol (o-aminophenol) Center: 3-Aminophenol (m-aminophenol) Right: 4-Aminophenol (p-aminophenol) Aminophenol may refer to any of three isomeric chemical compounds: 2-Aminophenol; 3-Aminophenol; 4-Aminophenol; They are simultaneously an aniline and a phenol
Codeine/paracetamol, also called codeine/acetaminophen and co-codamol, is a compound analgesic, comprising codeine phosphate and paracetamol (acetaminophen). Codeine/paracetamol is used for the relief of mild to moderate pain when paracetamol or non-steroidal anti-inflammatory drugs (NSAIDs; such as ibuprofen, aspirin, and naproxen) alone do not sufficiently relieve symptoms.
[3] [4] Without treatment, death from toxicity occurs 4 to 18 days later. [5] Paracetamol poisoning can occur accidentally or as an attempt to die by suicide. Risk factors for toxicity include alcoholism, malnutrition, and the taking of certain other hepatotoxic medications. [1]