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Using animals to assess the effects of addiction and withdrawal was a relatively common practice during Deneau’s [1] time, with monkeys and rats being the most prevalent subjects. [20] [21] Notably, Charles Schuster’s studies on drug self-administration were critical in demonstrating the highly addictive nature of stimulant substances. [22]
Several non-human animal species are said to engage in apparent recreational drug use, that is, the intentional ingestion of psychoactive substances in their environment for pleasure, though claims of such behavior in the wild are often controversial. [1]
Zebrafish have also been used to test the medicinal benefits of certain psychoactive drugs, particularly how they can be used to treat mental health problems. [38] A study looking into the antidepressant properties of ketamine using zebrafish as subjects found that when exposed to small amounts of ketamine (2 mg/L), zebrafish displayed more ...
In the preference testing phase, the animal is allowed unrestricted access to all compartments of the apparatus. [17] During the test, the time a subject spends in each compartment is measured in seconds. [16] Modern protocols utilize commercial automated tracking systems to measure the time; however, manual measurement is also used.
Test your knowledge on all things zoology with these animal trivia questions about cats, dogs, fish, zoo animals and insects perfect for kids and adults. 100 animal trivia questions that will make ...
Rat Park was a series of studies into drug addiction conducted in the late 1970s and published between 1978 and 1981 by Canadian psychologist Bruce K. Alexander and his colleagues at Simon Fraser University in British Columbia, Canada.
The higher the frequency with which a test animal emits the operant behavior, the more rewarding (and addictive), the test substance is considered. Self-administration of addictive drugs has been studied using humans, [1] non-human primates, [2] mice, [3] invertebrates such as ants, and, most commonly, rats.
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