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Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B 3). [2] Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. [1] Areas of the skin exposed to friction and radiation are typically affected first. [1]
Niacin deficiency is a consequence of a diet low in both niacin and the amino acid tryptophan, a precursor for the vitamin. Low plasma tryptophan is a non-specific indicator, meaning it can have other causes. The signs and symptoms of niacin deficiency start to revert within days of oral supplementation with large amounts of the vitamin. [23] [24]
According to the World Health Organization, an alternative mean of expressing urinary N1-methyl-nicotinamide is as mg/g creatinine in a 24-hour urine collection, with deficient defined as <0.5, low 0.5-1.59, acceptable 1.6-4.29, and high >4.3 [11] Niacin deficiency occurs before the signs and symptoms of pellagra appear. [6]
Hypolipidemia is when your lipid levels are too low. You might not notice any ongoing symptoms of dyslipidemia, but it can lead to serious health conditions if left untreated. ... Niacin. PCSK9 ...
Micronutrient deficiencies are considered a public health problem worldwide. For over 30 years it has been estimated that more than two billion people of all ages are affected by this burden, [1] while a recently published study based on individual-level biomarker data estimated that there are 372 million children aged 5 years and younger, and 1.2 billion non-pregnant women of reproductive age ...
Biotin deficiency rarely occurs among healthy people because the daily requirement of biotin is low, many foods provide adequate amounts of it, intestinal bacteria synthesize small amounts of it, and the body effectively scavenges and recycles it in the kidneys during production of urine.
The research team's leader, Dr. Stanley Hazen, said 1 in 4 subjects in the study were found to be getting too much niacin, and, therefore had high levels of 4PY and a higher risk of cardiovascular ...
Normal potassium levels are between 3.5 and 5.0 mmol/L (3.5 and 5.0 mEq/L) with levels below 3.5 mmol/L defined as hypokalemia. [21] [28] It is classified as severe when levels are less than 2.5 mmol/L. [21] Low levels may also be suspected based on an electrocardiogram (ECG). [21] Hyperkalemia is a high level of potassium in the blood serum. [21]