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  2. Vitamin deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_deficiency

    Niacin deficiency is a consequence of a diet low in both niacin and the amino acid tryptophan, a precursor for the vitamin. Low plasma tryptophan is a non-specific indicator, meaning it can have other causes. The signs and symptoms of niacin deficiency start to revert within days of oral supplementation with large amounts of the vitamin. [23] [24]

  3. Pellagra - Wikipedia

    en.wikipedia.org/wiki/Pellagra

    Chronic alcoholism can also cause poor absorption, which combined with a diet already low in niacin and tryptophan produces pellagra. [10] Hartnup disease is a genetic disorder that reduces tryptophan absorption, leading to pellagra. Alterations in protein metabolism may also produce pellagra-like symptoms.

  4. Niacin - Wikipedia

    en.wikipedia.org/wiki/Niacin

    A man with pellagra, which is caused by a chronic lack of vitamin B 3 in the diet. Severe deficiency of niacin in the diet causes the disease pellagra, characterized by diarrhea, sun-sensitive dermatitis involving hyperpigmentation and thickening of the skin (see image), inflammation of the mouth and tongue, delirium, dementia, and if left untreated, death. [7]

  5. Dyslipidemia: What Happens When Your Blood Fat Levels Are Off?

    www.aol.com/dyslipidemia-happens-blood-fat...

    Dyslipidemia is when the lipids in your blood are too high or too low. Estimates suggest that 53 percent of adults in the U.S. have lipid abnormalities.

  6. Micronutrient deficiency - Wikipedia

    en.wikipedia.org/wiki/Micronutrient_deficiency

    Micronutrient deficiencies are considered a public health problem worldwide. For over 30 years it has been estimated that more than two billion people of all ages are affected by this burden, [1] while a recently published study based on individual-level biomarker data estimated that there are 372 million children aged 5 years and younger, and 1.2 billion non-pregnant women of reproductive age ...

  7. Vitamin Once Prescribed to Lower Heart Disease Risk May ...

    www.aol.com/lifestyle/vitamin-once-prescribed...

    At higher doses, niacin has been used to treat high cholesterol and triglyceride levels, since it can help lower LDL (“bad”) cholesterol and raise levels of HDL (“good”) cholesterol.

  8. Hartnup disease - Wikipedia

    en.wikipedia.org/wiki/Hartnup_disease

    Hartnup disease (also known as "pellagra-like dermatosis" [1] and "Hartnup disorder" [2]) is an autosomal recessive [3] metabolic disorder affecting the absorption of nonpolar amino acids (particularly tryptophan that can be, in turn, converted into serotonin, melatonin, and niacin).

  9. Leucine - Wikipedia

    en.wikipedia.org/wiki/Leucine

    Leucine toxicity, as seen in decompensated maple syrup urine disease, causes delirium and neurologic compromise, and can be life-threatening. [20] A high intake of leucine may cause or exacerbate symptoms of pellagra in people with low niacin status because it interferes with the conversion of L-tryptophan to niacin. [21]

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