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Within the general subject of organic synthesis, there are many different types of synthetic routes that can be completed including total synthesis, [1] stereoselective synthesis, [2] automated synthesis, [3] and many more. Additionally, in understanding organic synthesis it is necessary to be familiar with the methodology, techniques, and ...
Hantzsch pyridine synthesis, Gattermann–Skita synthesis, Guareschi–Thorpe condensation, Knoevenagel–Fries modification Hantzsch–Collidin synthesis Harries ozonolysis
Synthetic organic chemistry is an applied science as it borders engineering, the "design, analysis, and/or construction of works for practical purposes". [28] Organic synthesis of a novel compound is a problem-solving task, where a synthesis is designed for a target molecule by selecting optimal reactions from optimal starting materials.
Retrosynthetic analysis is a technique for solving problems in the planning of organic syntheses.This is achieved by transforming a target molecule into simpler precursor structures regardless of any potential reactivity/interaction with reagents.
Additionally, synthesis aids natural product research by helping confirm and elucidate the structures of newly isolated compounds. The field of natural product synthesis has progressed remarkably since the early 19th century, with improvements in synthetic techniques, analytical methods, and an evolving understanding of chemical reactivity. [7]
The split-mix method can be used for the synthesis of organic or any other kind of library that can be prepared from its building blocks in a stepwise process. In 1990 three groups described methods for preparing peptide libraries by biological methods [ 15 ] [ 16 ] [ 17 ] and one year later Fodor et al. published a remarkable method for ...
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