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The term seizure threshold is used to describe the balance between excitatory (glutaminergic) and inhibitory (GABA-ergic) forces in the brain which affect how susceptible a person is to seizures. Those diagnosed with epilepsy or certain other neurological conditions are more vulnerable to seizures if the threshold is reduced, and should be ...
Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid used medically to treat chronic pain and opioid use disorder. [7] Prescribed for daily use, the medicine relieves cravings and opioid withdrawal symptoms. [10]
Surviving dogs developed seizures, fecal and urinary incontinence, confusion, memory loss, seromas, emotional dysregulation, focal neurologic symptoms, weakness, and weight loss. [19] 40% of surviving dogs did not have a reduction in existing aggression, and some dogs' aggression worsened after the procedure. [19] The treatments were described ...
Levels further down the Racine stages also contain symptoms of the previous stages. For example, an animal that is demonstrating the actions of a stage four seizure may also demonstrate head nodding (indicative of a level two seizure). [3] It is known that repeated exposure to a stimuli lowers the overall threshold for a seizure.
[67] [78] [79] [80] Some antipsychotic agents may be riskier than others during withdrawal, especially clozapine, olanzapine or low potency phenothiazines (e.g., chlorpromazine), as they lower the seizure threshold and can worsen withdrawal effects; if used, extreme caution is required. [81]
Similar to fentanyl, a highly potent synthetic opioid, methadone stimulates opioid receptors, making it possible to overdose on the medication, said Matthew Rogalski, an addiction medicine ...
Opioid-induced hyperalgesia (OIH) or opioid-induced abnormal pain sensitivity, also called paradoxical hyperalgesia, is an uncommon condition of generalized pain caused by the long-term use of high dosages of opioids [1] such as morphine, [2] oxycodone, [3] and methadone.
1. Ketogenic Diet. Cancer cells rely on glucose for energy to grow. The ketogenic diet is a way to provide an alternative energy source to normal cells in the dog's body while starving the cancer ...