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The American Cancer Society reports 5-year relative survival rates of over 70% for women with stage 0-III breast cancer with a 5-year relative survival rate close to 100% for women with stage 0 or stage I breast cancer. The 5-year relative survival rate drops to 22% for women with stage IV breast cancer. [3]
Cancer mortality rates are determined by the relationship of a population's health and lifestyle with their healthcare system. In the United States during 2013–2017, the age-adjusted mortality rate for all types of cancer was 189.5/100,000 for males, and 135.7/100,000 for females. [ 1 ]
Typically, cancer five-year relative survival rates are well below 100%, reflecting excess mortality among cancer patients compared to the general population. In contrast to five-year absolute survival rates, five-year relative survival rates may also equal or even exceed 100% if cancer patients have the same or even higher survival rates than ...
The American Cancer Society report also showed good news: Breast cancer mortality rates have dropped by 44% since 1989, which translates to approximately 517,900 fewer women dying during this time ...
The five-year survival rates in England and the United States are between 80 and 90%. [16] [4] [5] In developing countries, five-year survival rates are lower. [2] Worldwide, breast cancer is the leading type of cancer in women, accounting for 25% of all cases. [17] In 2018, it resulted in two million new cases and 627,000 deaths. [18]
Triple-negative breast cancer comprises 15–20% of all breast cancer cases [3] and affects more young women or women with a mutation in the BRCA1 gene than other breast cancers. [4] Triple-negative breast cancers comprise a very heterogeneous group of cancers. TNBC is the most challenging breast cancer type to treat. [5]
The Nottingham prognostic index (NPI) is used to determine prognosis following surgery for breast cancer. [1] [2] Its value is calculated using three pathological criteria: the size of the tumour; the number of involved lymph nodes; and the grade of the tumour. [1] It is calculated to select patients for adjuvant treatment.
Metastatic breast cancer can be treated, sometimes for many years, but it cannot be cured. [2] Distant metastases are the cause of about 90% of deaths due to breast cancer. [3] Breast cancer can metastasize anywhere in body but primarily metastasizes to the bone, lungs, regional lymph nodes, liver and brain, with the most common site being the ...
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