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How it works is not clear, but it may involve blocking certain adrenergic and serotonin receptors. [11] [12] Chemically, it is a tetracyclic antidepressant, [12] and is closely related to mianserin. It also has strong antihistaminergic effects. [11] [12] Mirtazapine came into medical use in the United States in 1996. [12]
Medication for Anxiety: A Complete Guide. As you probably know from personal experience, anxiety can be a lot of things — a cause of insomnia, a roadblock to living your best life or a demon you ...
Medications for Depression: An Overview. Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used ...
Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]
Key symptoms include excessive anxiety about multiple events and issues, and difficulty controlling worrisome thoughts, that persists for at least 6 months. Antidepressants provide a modest-to-moderate reduction in anxiety in GAD, [25] and are superior to placebo in treating GAD. The efficacy of different antidepressants is similar.
Before the 1950s, opioids and amphetamines were commonly used as antidepressants. [266] [267] [196] Amphetamine has been described as the first antidepressant. [196] Use of opioids and amphetamines for depression was later restricted due to their addictive nature and side effects.
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