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Azelastine, sold under the brand name Astelin among others, is a H 1 receptor-blocking medication primarily used as a nasal spray to treat allergic rhinitis (hay fever) and as eye drops for allergic conjunctivitis. [5] [6] Other uses may include asthma and skin rashes for which it is taken by mouth. [7]
Combination use of two medications as nasal spray preparation has been frequently prescribed by doctors. [medical citation needed] List of some combination nasal sprays: Azelastine together with fluticasone propionate (brand names including Dymista) [4] Xylometazoline together with cromoglicic acid
ATC code R01 Nasal preparations is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. [1] [2] [3] Subgroup R01 is part of the anatomical group R Respiratory system. [4]
Fluticasone propionate, sold under the brand names Flovent and Flonase among others, is a glucocorticoid steroid medication. [8] When inhaled it is used for the long term management of asthma and COPD. [8] In the nose it is used for hay fever and nasal polyps. [9] [10] It can also be used for mouth ulcers. [11] It works by decreasing inflammation.
As inhalers they are used to treat asthma, as nasal sprays to treat hay fever (allergic rhinitis) and as eye drops for allergic conjunctivitis. [2] Finally, in oral form, they are used to treat the rare condition of mastocytosis .
An experimental nasal spray has helped clear toxic protein buildups in the brains of mouse models of Alzheimer's. Its developers believe the spray may help delay Alzheimer's by at least a decade.
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