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AOH1996 is an experimental anticancer medication which acts as a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) and is in Phase I clinical trials at City of Hope as of August 2023 for the treatment of solid tumors. [1] [2] [3] [4]
The Mays Cancer Center's Institute for Drug Development (IDD) is internationally recognized for conducting one of the largest oncology Phase I clinical drug trials programs in the world. Fifteen of the cancer drugs most recently approved by the U.S. Food & Drug Administration underwent development or testing at the IDD.
[18] [17] [15] As of 2023, MD Anderson Cancer Center is home to the highest number of cancer clinical trials in the world and has received more NCI-funded projects than any other U.S. institute. [19] [20] For 2024, Newsweek placed MD Anderson at #1 in their annual list of the World's Best Specialized Hospitals in oncology. [21]
The Alliance for Clinical Trials in Oncology is a national clinical trials network sponsored by the National Cancer Institute (NCI) that consists of about 10,000 cancer specialists at hospitals, medical centers, and community clinics across the United States and Canada. [1]
The DRKS is an open access, free of charge online register for clinical trials and is available both in English and German. DRKS is part of the WHO's ICTRP. The DRKS works with two partner registries in Germany, DeReG (German Registry for Somatic Gene-Transfer Trials) and Clinical Trial Registry of the University Medical Center Freiburg. [4]
Cassava Sciences was founded by Remi Barbier in May 1998 as Pain Therapeutics, [3] [4] focusing on opioids and chronic pain. [5] Barbier first heard of the research led by Stanley M. Crain at the Albert Einstein College of Medicine in New York City around 1993. [5]
As a result of pressure from HIV-infected men in the gay community, [citation needed] who demanded better access to clinical trials, the U.S. Congress passed the Health Omnibus Programs Extension Act of 1988 (Public Law 100-607) [2] which mandated the development of a database of AIDS Clinical Trials Information Services (ACTIS). [3]
Synergyst Research launched a spin-off company, Discovery Clinical Trials, in 2009. The company helps Synergyst clients develop and manage new research departments. [ 1 ] In November 2012 the two companies combined were named for a second year in a row on the 5000 List of "America's Fastest-Growing Private Companies," ranking No. 145 among ...
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