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  2. Cell damage - Wikipedia

    en.wikipedia.org/wiki/Cell_damage

    The most notable components of the cell that are targets of cell damage are the DNA and the cell membrane. DNA damage: In human cells, both normal metabolic activities and environmental factors such as ultraviolet light and other radiations can cause DNA damage, resulting in as many as one million individual molecular lesions per cell per day. [5]

  3. Cellular stress response - Wikipedia

    en.wikipedia.org/wiki/Cellular_stress_response

    Early research has suggested that cells which are better able to synthesize stress proteins and do so at the appropriate time are better able to withstand damage caused by ischemia and reperfusion. [15] In addition, many stress proteins overlap with immune proteins. These similarities have medical applications in terms of studying the structure ...

  4. Stress fracture - Wikipedia

    en.wikipedia.org/wiki/Stress_fracture

    A stress fracture is a fatigue-induced bone fracture caused by repeated stress over time. Instead of resulting from a single severe impact, stress fractures are the result of accumulated injury from repeated submaximal loading, such as running or jumping. Because of this mechanism, stress fractures are common overuse injuries in athletes. [1]

  5. Heat shock protein - Wikipedia

    en.wikipedia.org/wiki/Heat_shock_protein

    Heat-shock proteins can be secreted from immune cells or tumour cells by non-canonical secretion pathway, or leaderless pathway, because they do not have the leader peptide, which navigate proteins into endoplasmic reticulum. The non-canonical secretion can be similar to the one, which occurs for IL1 b, and it is induced by stress conditions. [30]

  6. Bone resorption - Wikipedia

    en.wikipedia.org/wiki/Bone_resorption

    The bone becomes more porous and fragile, exposing people to the risk of fractures. Depending on where in the body bone resorption occurs, additional problems like tooth loss can arise. This can be caused by conditions such as hyperparathyroidism and hypovitaminosis D or even decreased hormonal production in the elderly.

  7. Stress fracture in your shin from running may require surgery ...

    www.aol.com/stress-fracture-shin-running-may...

    A stress fracture is an overuse injury that is caused by repetitive micro trauma exceeding the strength of a bone. Some stress fractures can heal with rest or immobilization.

  8. Oxidative stress - Wikipedia

    en.wikipedia.org/wiki/Oxidative_stress

    Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]

  9. Today's Wordle Hint, Answer for #1249 on Tuesday, November 19 ...

    www.aol.com/todays-wordle-hint-answer-1249...

    If you’re stuck on today’s Wordle answer, we’re here to help—but beware of spoilers for Wordle 1249 ahead. Let's start with a few hints.