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Peribronchial cuffing, also referred to as peribronchial thickening or bronchial wall thickening, is a radiologic sign which occurs when excess fluid or mucus buildup in the small airway passages of the lung causes localized patches of atelectasis (lung collapse). [1] This causes the area around the bronchus to appear more prominent on an X-ray ...
In both CT and chest radiographs, normal lungs appear dark due to the relative lower density of air compared to the surrounding tissues. When air is replaced by another substance (e.g. fluid or fibrosis), the density of the area increases, causing the tissue to appear lighter or more grey.
It also includes lung manifestations of autoimmune diseases such as Sjögren syndrome or rheumatoid arthritis. [ 3 ] [ 4 ] Histopathologic studies have shown that the tree-in-bud pattern is caused by demarcation of the normally invisible branching course of the peripheral airways, which usually results from bronchioles being plugged or blocked ...
Mild peribronchial cuffing as seen in viral bronchitis. A physical examination will often reveal decreased intensity of breath sounds, wheezing, rhonchi, and prolonged expiration. During examination, physicians rely on history and the presence of persistent or acute onset of cough, followed by a URTI with no traces of pneumonia.
The differential diagnosis includes other types of lung disease that cause similar symptoms and show similar abnormalities on chest radiographs. Some of these diseases cause fibrosis, scarring or honeycomb change. The most common considerations include: chronic hypersensitivity pneumonitis; non-specific interstitial pneumonia; sarcoidosis
Bronchiolitis obliterans (BO), also known as obliterative bronchiolitis, constrictive bronchiolitis and popcorn lung, is a disease that results in obstruction of the smallest airways of the lungs (bronchioles) due to inflammation. [1] [6] Symptoms include a dry cough, shortness of breath, wheezing and feeling tired. [1]
Airway inflammation is increased during the exacerbation resulting in increased hyperinflation, reduced expiratory air flow and decreased gas exchange. [1] [2] Exacerbations can be classified as mild, moderate, and severe. [3] As COPD progresses, exacerbations tend to become more frequent, the average being about three episodes per year. [4]
The mechanism of disease is breakdown of the airways due to an excessive inflammatory response. [3] Involved airways ( bronchi ) become enlarged and thus less able to clear secretions. [ 3 ] These secretions increase the amount of bacteria in the lungs, resulting in airway blockage and further breakdown of the airways. [ 3 ]