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When you have high blood pressure, your heart and blood vessels have to work harder to make blood flow through your body. This is pretty much the opposite of what sildenafil does — as a reminder ...
A word on sildenafil drug interactions: Mixing antihypertensive prescription drugs (hypertension meds) with Viagra may cause low blood pressure. Since the medication has blood pressure-lowering ...
All currently available ED medications can temporarily cause slightly lower blood pressure levels, thanks to their effects on smooth muscle tissue and blood flow. This low blood pressure is most ...
Sildenafil should not be taken by people on nitric oxide donors such as nitroglycerin (glycerin trinitrate), as this may result in a serious drop in blood pressure. [8] Sildenafil acts by blocking phosphodiesterase 5 (PDE 5), an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. [8]
Viagra or sildenafil, the active ingredient and generic version, is a PDE-5 inhibitor that widens blood vessels inside the member to allow better blood flow for stronger or longer-lasting arousal.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
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