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Selenium at nutritional levels is required for cell homeostasis, playing a role as an anti-oxidant through selenoproteins, thus, act chemo-preventive against cancer. In contrast, supra-nutritional levels act as pro-oxidant toxic in tumour cells. [39] Selenium has bimodal biological action
Selenium : 60–150 ng/mL ... Maintain calcium and phosphorus levels ... Needed for nerve cells, red blood cells, and to make DNA 6-14 ...
Selenium at nutritional levels or low concentrations is required for cell homeostasis, playing a role as an anti-oxidant through selenoproteins, thus, act chemo-preventive against cancer. In contrast, supra-nutritional levels or higher concentrations act as pro-oxidant in tumour cells, thus can be exploited as chemo-therapeutic against cancer .
In humans, arsenic is toxic, and its levels in foods and dietary supplements are closely ... Selenium toxicity ... % cell count Erythrocytes (red blood cells) 4.2 85. ...
Selenium deficiency occurs when an organism lacks the required levels of selenium, a critical nutrient in many species.Deficiency, although relatively rare in healthy well-nourished individuals, [1] can have significant negative results, [2] affecting the health of the heart and the nervous system; contributing to depression, anxiety, and dementia; and interfering with reproduction and gestation.
Selenium is a vital nutrient in animals, [7] including humans. About 25 different selenocysteine-containing selenoproteins have so far been observed in human cells and tissues. [ 8 ] Since lack of selenium deprives the cell of its ability to synthesize selenoproteins, many health effects of low selenium intake are believed to be caused by the ...
When cells are grown in the absence of selenium, translation of selenoproteins terminates at the UGA codon, resulting in a truncated, nonfunctional enzyme. The UGA codon is made to encode selenocysteine by the presence of a selenocysteine insertion sequence (SECIS) in the mRNA. The SECIS element is defined by characteristic nucleotide sequences ...
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
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