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False negative readings can occur when testing is done too early. hCG levels rise rapidly in early pregnancy and the chances of false negative test results diminish with time (increasing gestational age). [24] Less sensitive urine tests and qualitative blood tests may not detect pregnancy until three or four days after implantation. [25]
The false positive rate (FPR) is the proportion of all negatives that still yield positive test outcomes, i.e., the conditional probability of a positive test result given an event that was not present. The false positive rate is equal to the significance level. The specificity of the test is equal to 1 minus the false positive rate.
However, the test does have limitations. If the test is performed early during the first trimester there is a chance that it can yield false negative or positive results, and false positive results may cause unnecessary worry for prospective parents.
A pregnancy test detects the presence of the pregnancy hormone human chorionic gonadotropin in a person’s body. The body doesn’t produce that hormone until several days after conception.
Pregnancy tests are not accurate until 1–2 weeks after ovulation. Knowing an estimated date of ovulation can prevent a woman from getting false negative results due to testing too early. Also, 18 consecutive days of elevated temperatures means a woman is almost certainly pregnant. [61]
Other screening tests, such as the Quad test, can also have false positives and false negatives. Even when the Quad results are positive (or, to be more precise, when the Quad test yields a score that shows at least a 1 in 270 risk of abnormality), usually the pregnancy is normal, but additional diagnostic tests are offered.
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