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Serratus is a large scale viroinformatics platform for uncovering the total genetic diversity of Earth's virome.Originating with the goal of uncovering novel coronaviruses [1] that may have been incidentally sequenced by other researchers, the project expanded to encompass all RNA viruses, those which encode a viral RNA-dependent RNA polymerase (RdRp).
Viruses are the most abundant biological entities on Earth, but challenges in detecting, isolating, and classifying unknown viruses have prevented exhaustive surveys of the global virome. [25] Over 5 Tb of metagenomic sequence data were used from 3,042 geographically diverse samples to assess the global distribution, phylogenetic diversity, and ...
Some of Kyrpides's recent research in microbiome data science include the exploration of Earth’s virome, [25] [26] the identification of new bacterial phyla [27] the prediction of novel folds using metagenomic sequences, [28] and the discovery and characterization of new protein families from microbiome data. [29]
Virosphere (virus diversity, virus world, global virosphere) was coined to refer to all those places in which viruses are found or which are affected by viruses. [1] [2] However, more recently virosphere has also been used to refer to the pool of viruses that occurs in all hosts and all environments, [3] as well as viruses associated with specific types of hosts (prokaryotic virosphere, [4 ...
[3] The goal of the Global Virome Project (GVP) is to identify and prevent future virus outbreaks. [4] The GVP is centered on the massive collection and sequencing of the planet's unknown viruses, with an estimated 1.6 million viral species yet to be discovered in mammal and bird populations. Of these, 631,000 to 827,000 have zoonotic potential ...
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The virome of each individual is viewed by looking at the black bars in a given column. [16] Each individual had a distinct viral profile, demonstrating the high interpersonal diversity of the virome. One to 15 viral genera (average 5.5) were detected in 92% of the 102 individuals sampled (Figure 2). [16]
The names of realms consist of a descriptive first part and the suffix -viria, which is the suffix used for virus realms. [1] The first part of Duplodnaviria means "double DNA", referring to dsDNA viruses, [2] the first part of Monodnaviria means "single DNA", referring to ssDNA viruses, [3] the first part of Riboviria is taken from ribonucleic acid (RNA), [4] and the first part of ...