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  2. Chiral drugs - Wikipedia

    en.wikipedia.org/wiki/Chiral_drugs

    Louis Pasteur - pioneering stereochemist. Chirality can be traced back to 1812, when physicist Jean-Baptiste Biot found out about a phenomenon called "optical activity." [10] Louis Pasteur, a famous student of Biot's, made a series of observations that led him to suggest that the optical activity of some substances is caused by their molecular asymmetry, which makes nonsuperimposable mirror ...

  3. Chiral switch - Wikipedia

    en.wikipedia.org/wiki/Chiral_switch

    Chiral switching strategy is the way most blockbuster drugs have entered the market as enantiopure drugs. A more appropriate term may be unichiral. [29] [30] But the alternate route is de novo (anew) synthesis of chiral specific drugs. [31] The chiral switches may have the same, very similar, therapeutic indications as the original racemic drug.

  4. Enantiopure drug - Wikipedia

    en.wikipedia.org/wiki/Enantiopure_drug

    An enantiopure drug is a pharmaceutical that is available in one specific enantiomeric form. Most biological molecules (proteins, sugars, etc.) are present in only one of many chiral forms, so different enantiomers of a chiral drug molecule bind differently (or not at all) to target receptors. Chirality can be observed when the geometric ...

  5. Diabetes medication - Wikipedia

    en.wikipedia.org/wiki/Diabetes_medication

    Drugs used in diabetes treat types of diabetes mellitus by decreasing glucose levels in the blood. With the exception of insulin , most GLP-1 receptor agonists ( liraglutide , exenatide , and others), and pramlintide , all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents.

  6. Pioglitazone - Wikipedia

    en.wikipedia.org/wiki/Pioglitazone

    Pioglitazone, sold under the brand name Actos among others, is an anti-diabetic medication used to treat type 2 diabetes. [3] It may be used with metformin, a sulfonylurea, or insulin. [3] [4] Use is recommended together with exercise and diet. [4] It is not recommended in type 1 diabetes. [4] It is taken by mouth. [4]

  7. Medicare costs significantly lowered on popular prescription ...

    www.aol.com/finance/medicare-costs-significantly...

    Here is the list of drugs, the condition they treat, the 2026 pricing for a 30-day supply of each drug, and the discount off the list price: Eliquis Conditions: Prevention and treatment of blood clots

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