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  2. Rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Rosuvastatin

    Common side effects include abdominal pain, nausea, headaches, and muscle pains. [6] Serious side effects may include rhabdomyolysis, liver problems, and diabetes. [6] Use during pregnancy may harm the baby. [6] Like all statins, rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing ...

  3. JUPITER trial - Wikipedia

    en.wikipedia.org/wiki/JUPITER_trial

    Reports of serious adverse events within JUPITER were equally distributed between the study's rosuvastatin and placebo arms. There were no significant differences between the treatment groups with respect to muscle pain, muscle weakness, hepatic function, or renal function; however, the researchers noted small but statistically significant increases in the rate of physician-reported diabetes ...

  4. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    The U.S. Food and Drug Administration (FDA) notified healthcare professionals of updates to the prescribing information concerning interactions between protease inhibitors and certain statin drugs. Protease inhibitors and statins taken together may increase the blood levels of statins and increase the risk for muscle injury (myopathy).

  5. Ezetimibe/rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Ezetimibe/rosuvastatin

    Ezetimibe/rosuvastatin, sold under the brand name Ridutrin among others, is a combination medication used to treat high cholesterol. [6] [7] In some countries it is sold as a kit or a pack containing two distinct pills. [8] [9] The combination was approved for medical use in the United States in March 2021. [4]

  6. 3-in-1 blood pressure drug may be more effective than current ...

    www.aol.com/3-1-blood-pressure-drug-142000727.html

    A new pill combining low doses of three different anti-hypertensive medications surpassed the standard care for high blood pressure using one anti-hypertensive drug, a new study showed.

  7. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...

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  9. Fluvastatin - Wikipedia

    en.wikipedia.org/wiki/Fluvastatin

    The drug is quickly and almost completely (98%) absorbed from the gut. Food intake slows down absorption, but does not decrease it. Due to its first-pass effect, bioavailability is lower: about 24–30% [2] [1] according to different sources. Over 98% of the substance is bound to plasma proteins. [1]

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