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  2. Selective immunoglobulin A deficiency - Wikipedia

    en.wikipedia.org/wiki/Selective_immunoglobulin_A...

    Selective immunoglobulin A (IgA) deficiency (SIgAD [1]) is a kind of immunodeficiency, a type of hypogammaglobulinemia. People with this deficiency lack immunoglobulin A (IgA), a type of antibody that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract.

  3. Hypogammaglobulinemia - Wikipedia

    en.wikipedia.org/wiki/Hypogammaglobulinemia

    Hypogammaglobulinemia may result from a variety of primary genetic immune system defects, such as common variable immunodeficiency, [1] or it may be caused by secondary effects such as medication, blood cancer, or poor nutrition, or loss of gamma globulins in urine, as in nonselective glomerular proteinuria.

  4. Immunoglobulin A - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_A

    Decreased or absent IgA due to an inherited inability to produce IgA is termed selective IgA deficiency and can produce a clinically significant immunodeficiency. [ 20 ] Anti-IgA antibodies, sometimes present in individuals with low or absent IgA, can result in serious anaphylactic reactions when transfused with blood products that incidentally ...

  5. Immunodeficiency - Wikipedia

    en.wikipedia.org/wiki/Immunodeficiency

    Immunodeficiency, also known as immunocompromisation, is a state in which the immune system's ability to fight infectious diseases and cancer is compromised or entirely absent. Most cases are acquired ("secondary") due to extrinsic factors that affect the patient's immune system.

  6. Common variable immunodeficiency - Wikipedia

    en.wikipedia.org/wiki/Common_variable...

    Common variable immunodeficiency (CVID) is an inborn immune disorder characterized by recurrent infections and low antibody levels, specifically in immunoglobulin (Ig) types IgG, IgM, and IgA. [2] Symptoms generally include high susceptibility to pathogens, chronic lung disease, as well as inflammation and infection of the gastrointestinal ...

  7. It is characterized by variable reductions in serum immunoglobulin (IgG, IgM and/or IgA) levels which cause most ICF patients to succumb to infectious diseases before adulthood. ICF syndrome patients exhibit facial anomalies which include hypertelorism, low-set ears, epicanthal folds and macroglossia. [3]

  8. Primary immunodeficiency - Wikipedia

    en.wikipedia.org/wiki/Primary_immunodeficiency

    IgA deficiency is an exception, and is present in 1 in 500 people. Some of the more frequently seen forms of PID include common variable immunodeficiency, severe combined immunodeficiency, X-linked agammaglobulinemia, Wiskott–Aldrich syndrome, DiGeorge syndrome, ataxia–telangiectasia, [11]

  9. Dysgammaglobulinemia - Wikipedia

    en.wikipedia.org/wiki/Dysgammaglobulinemia

    IgG deficiency - IgG deficiency is a lack of IgG in the absence of other immunoglobulin deficiencies. IgG levels of 300–600 mg/dL show a mild to moderate reduction of IgG while levels below 200 mg/dl are classified as a severe deficiency. [6] Those with IgG deficiency often get chronic or reoccurring pyogenic respiratory tract infections. [7]

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