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A number of specific antibodies found in the blood (antinuclear antibody (ANA), anti-smooth muscle antibody (SMA), anti-liver kidney microsomal antibodies (LKM-1, LKM-2, LKM-3), anti soluble liver antigen (SLA), liver–pancreas antigen (LP), and anti-mitochondrial antibody (AMA)) are of use, as is finding an increased immunoglobulin G level.
Anti-smooth muscle antibodies are antibodies (immunoglobulins) formed against smooth muscle. These antibodies are typically associated with autoimmune hepatitis. [1] [2] These antibodies can be directed against actin, troponin, and tropomyosin. [3]
Anti-neutrophil cytoplasmic antibody: c-ANCA: proteins in neutrophil cytoplasm: granulomatosis with polyangiitis: p-ANCA: neutrophil perinuclear: microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis, systemic vasculitides (non-specific) Rheumatoid factor: IgG: rheumatoid arthritis: Anti-smooth muscle antibody: smooth muscle ...
Antinuclear antibodies and anti-smooth muscle antibody are found in 20-50% of PSC patients, and likewise are not specific for the disease, but may identify a subgroup of PSC patients who also have autoimmune hepatitis (i.e. PSC-AIH overlap syndrome). [4]
Anti-actin antibodies; Anti-dsDNA antibodies; Anti-glomerular basement membrane antibody; Anti-glutamate receptor antibodies; Anti-histone antibodies; Anti-Jo1; Anti-neutrophil cytoplasmic antibody; Anti-nRNP; Anti-Scl-70 antibodies; Anti-smooth muscle antibody; Anti-sp100 antibodies; Anti-SSA/Ro autoantibodies; Antisperm antibodies ...
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Anti-mitochondrial antibodies (AMA) are autoantibodies, consisting of immunoglobulins formed against mitochondria, [1] primarily the mitochondria in cells of the liver.. The presence of AMA in the blood or serum of a person may be indicative of the presence of, or the potential to develop, the autoimmune disease primary biliary cholangitis (PBC; previously known as primary biliary cirrhosis).
Testosterone is an essential hormone for both men and women, playing an important role in muscle growth and cognitive function. Low levels of the hormone can lead to changes in mood, cognition and ...
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