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  2. Systemic inflammation - Wikipedia

    en.wikipedia.org/wiki/Systemic_inflammation

    The cytokine Interleukin 6 and C-reactive protein are common inflammatory markers used to diagnose systemic inflammation risk. [3] Baseline C-reactive protein levels deviate due to natural genetic variation, but significant increases can result from risk factors such as smoking, obesity, lifestyle, and high blood pressure. [3]

  3. Biomarker (medicine) - Wikipedia

    en.wikipedia.org/wiki/Biomarker_(medicine)

    For example, body temperature is a well-known biomarker for fever. Blood pressure is used to determine the risk of stroke. It is also widely known that cholesterol values are a biomarker and risk indicator for coronary and vascular disease, and that C-reactive protein is a marker for inflammation.

  4. Biomarker - Wikipedia

    en.wikipedia.org/wiki/Biomarker

    In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues [ 1 ] to examine normal biological processes , pathogenic processes, or pharmacologic responses to a therapeutic intervention . [ 2 ]

  5. Elevated alkaline phosphatase - Wikipedia

    en.wikipedia.org/wiki/Elevated_alkaline_phosphatase

    Gastrointestinal inflammationinflammatory bowel disease (ulcerative colitis, Crohn's disease) or ulcers) [14] Rheumatoid arthritis; Ankylosing Spondylitis; Transient hyperphosphatasaemia of infancy: benign, transient, often associated with infection; Seminoma [15] Celiac disease [16] Sarcoidosis [17] Syphilis [18] Having B or O blood type ...

  6. Cytokine release syndrome - Wikipedia

    en.wikipedia.org/wiki/Cytokine_release_syndrome

    CRS occurs when large numbers of white blood cells, including B cells, T cells, natural killer cells, macrophages, dendritic cells, and monocytes are activated and release inflammatory cytokines, which activate more white blood cells in a positive feedback loop of pathogenic inflammation. [5]

  7. Inflammation - Wikipedia

    en.wikipedia.org/wiki/Inflammation

    Leukocytosis is often seen during inflammation induced by infection, where it results in a large increase in the amount of leukocytes in the blood, especially immature cells. Leukocyte numbers usually increase to between 15 000 and 20 000 cells per microliter, but extreme cases can see it approach 100 000 cells per microliter. [ 10 ]

  8. Acute-phase protein - Wikipedia

    en.wikipedia.org/wiki/Acute-phase_protein

    Inflammatory cells and red blood cells. Acute-phase proteins (APPs) are a class of proteins whose concentrations in blood plasma either increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation. This response is called the acute-phase reaction (also called acute-phase response).

  9. Arterial stiffness - Wikipedia

    en.wikipedia.org/wiki/Arterial_stiffness

    Inflammation plays a major role in arteriosclerosis development, and consequently it is a major contributor in large arteries stiffening. [2] Increased arterial stiffness is associated with an increased risk of cardiovascular events such as myocardial infarction , hypertension , heart failure , and stroke , two of the leading causes of death in ...