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  2. Human germline engineering - Wikipedia

    en.wikipedia.org/wiki/Human_germline_engineering

    The impact of human gene editing on resistance to HIV infection and other body functions in experimental infants remains controversial. The World Health Organization has issued three reports on the guidelines of human genome editing since 2019, [41] and the Chinese government has prepared regulations since May 2019. [42]

  3. Category:Genome editing - Wikipedia

    en.wikipedia.org/wiki/Category:Genome_editing

    This page was last edited on 17 December 2021, at 15:28 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.

  4. Genome editing - Wikipedia

    en.wikipedia.org/wiki/Genome_editing

    Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly inserts genetic material into a host genome, genome editing targets the insertions to site-specific locations.

  5. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    CRISPR-Cas9 genome editing techniques have many potential applications. The use of the CRISPR-Cas9-gRNA complex for genome editing [10] was the AAAS's choice for Breakthrough of the Year in 2015. [11] Many bioethical concerns have been raised about the prospect of using CRISPR for germline editing, especially in human embryos. [12]

  6. Genetic engineering techniques - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering_techniques

    The creation of HIV-resistant babies by Chinese researcher He Jiankui is perhaps the most famous example of gene disruption using this method. [68] It is far less effective at gene correction. Methods of base editing are under development in which a “nuclease-dead” Cas 9 endonuclease or a related enzyme is used for gene targeting while a ...

  7. Genetic editing - Wikipedia

    en.wikipedia.org/wiki/Genetic_editing

    Genetic editing is strong in European, particularly French and German, textual scholarship. The German genetic editing, which has been associated with synoptic telescoping, [4] has a different method of presentation from the Anglo-American model. [5] The primary model and test case of German editions has been Johann Wolfgang von Goethe.

  8. List of Nature Research journals - Wikipedia

    en.wikipedia.org/wiki/List_of_Nature_Research...

    This is a list of journals published by Nature Research. These include the flagship Nature journal, the Nature Reviews series (which absorbed the former Nature Clinical Practice series in 2009), the npj series, Scientific Reports and many others.

  9. Off-target genome editing - Wikipedia

    en.wikipedia.org/wiki/Off-target_genome_editing

    Off-target genome editing refers to nonspecific and unintended genetic modifications that can arise through the use of engineered nuclease technologies such as: clustered, regularly interspaced, short palindromic repeats ()-Cas9, transcription activator-like effector nucleases (), meganucleases, and zinc finger nucleases (ZFN). [1]