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Hyponatremia. Hyponatremia or hyponatraemia is a low concentration of sodium in the blood. [4] It is generally defined as a sodium concentration of less than 135 mmol/L (135 mEq/L), with severe hyponatremia being below 120 mEq/L. [3][8] Symptoms can be absent, mild or severe. [2][9] Mild symptoms include a decreased ability to think, headaches ...
[9] [3] Dilutional hyponatremia can happen in diabetics as high glucose levels pull water into the blood stream causing the sodium concentration to be lower. [9] [3] Diagnosis of the cause of hyponatremia relies on three factors: volume status, plasma osmolality, urine sodium levels and urine osmolality. [9] [3]
Hypernatremia, also spelled hypernatraemia, is a high concentration of sodium in the blood. [3] Early symptoms may include a strong feeling of thirst, weakness, nausea, and loss of appetite. [1] Severe symptoms include confusion, muscle twitching, and bleeding in or around the brain. [1][2] Normal serum sodium levels are 135–145 mmol/L (135 ...
High sodium consumption (5 g or more of salt per day) and insufficient potassium intake (less than 3.5 grams (0.12 oz) per day) have been linked to high blood pressure and increased risk of heart disease, stroke, and kidney disease. [5] [6] As an essential nutrient, sodium is involved in numerous cellular and organ functions. Several national ...
Acid–base and blood gases are among the few blood constituents that exhibit substantial difference between arterial and venous values. [6] Still, pH, bicarbonate and base excess show a high level of inter-method reliability between arterial and venous tests, so arterial and venous values are roughly equivalent for these.
Sodium is a chemical element; it has symbol Na (from Neo-Latin natrium) and atomic number 11. It is a soft, silvery-white, highly reactive metal. Sodium is an alkali metal, being in group 1 of the periodic table. Its only stable isotope is 23 Na. The free metal does not occur in nature and must be prepared from compounds.
While reduction of sodium intake to less than 2,300 mg per day is recommended by developed countries, [6] one review recommended that sodium intake be reduced to at least 1,200 mg (contained in 3 g of salt) per day, as a further reduction in salt intake led to a greater fall in systolic blood pressure for all age groups and ethnicities. [68]
Aldosterone is responsible for the reabsorption of about 2% of filtered sodium in the kidneys, which is nearly equal to the entire sodium content in human blood under normal glomerular filtration rates. [19] Aldosterone, probably acting through mineralocorticoid receptors, may positively influence neurogenesis in the dentate gyrus. [20]