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Gene structure is the organisation of specialised sequence elements within a gene.Genes contain most of the information necessary for living cells to survive and reproduce. [1] [2] In most organisms, genes are made of DNA, where the particular DNA sequence determines the function of the gene.
A structural gene is a gene that codes for any RNA or protein product other than a regulatory factor (i.e. regulatory protein).Structural genes are typically viewed as those containing sequences of DNA corresponding to the amino acids of a protein that will be produced, as long as said protein does not function to regulate gene expression.
Transcription factor 7-like 2 (T-cell specific, HMG-box), also known as TCF7L2 or TCF4, is a protein acting as a transcription factor that, in humans, is encoded by the TCF7L2 gene. [ 5 ] [ 6 ] The TCF7L2 gene is located on chromosome 10q25.2–q25.3, contains 19 exons .
Growth differentiation factor 9 (GDF9) is an oocyte derived growth factor in the transforming growth factor β (TGF-β) superfamily. [7] It is highly expressed in the oocyte and has a pivotal influence on the surrounding somatic cells, particularly granulosa, cumulus and theca cells. [7]
Neuregulin 1, or NRG1, is a gene of the epidermal growth factor family that in humans is encoded by the NRG1 gene. [3] [4] NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors.
A cistron is a region of DNA that is conceptually equivalent to some definitions of a gene, such that the terms are synonymous from certain viewpoints, [1] especially with regard to the molecular gene as contrasted with the Mendelian gene.
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, and ultimately affect a phenotype.
12155 Ensembl ENSG00000130385 ENSMUSG00000023279 UniProt O95972 Q9Z0L4 RefSeq (mRNA) NM_005448 NM_009757 RefSeq (protein) NP_005439 NP_033887 Location (UCSC) Chr X: 50.91 – 50.92 Mb Chr X: 6.23 – 6.23 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Bone morphogenetic protein 15 (BMP-15) is a protein that in humans is encoded by the BMP15 gene. It is involved in folliculogenesis ...