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Polysulfobetaines are zwitterionic polymers that contain a positively charged quaternary ammonium and a negatively charged sulfonate group within one constitutional repeat unit. [ 1 ] [ 2 ] In recent years, polysulfobetaines have received increasing attention owing to their good biotolerance and ultralow-fouling behavior towards surfaces.
Wetting solutions allow efficient spreading and wetting of the surface of skin and scalp by reducing the surface tension between the hydrophobic sebum secreted by the sebaceous gland in our skin. [8] An efficient wetting solution penetrates the skin and clears any topical applications, body fluids including sebum secreted via openings of hair ...
to stabilize proteins purified protein derivative (PPD) solution used in skin testing for tuberculosis exposure as a solubilizing agent of membrane proteins for lysing mammalian cells, at a concentration of 0.05% to 0.5% v/v, generally combined with other detergents, salts and additives.
Zwitterionic polymers have the ability to reduce nonspecific adsorption of proteins and cells at biological interfaces. Zwitterionic coatings are often used to minimize the negative effects of foreign body response for implanted devices and improve the device's biocompatibility.
Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy or for children with constipation. [6] Macrogol (with brand names such as Laxido, Movicol and Miralax) is the generic name for polyethylene glycol used as a laxative. The name may be followed by a number that ...
The exact gelling point varies depending on the properties of the gelator and the solvent, such as structure uniformity, molecular weight of the polymer, and flexibility of the polymer chain. [5] Generally, gels are prepared by firstly dissolving the soluble excipients in the solvent. [5] [3] The solution is then mixed using a mechanical ...
One molecule is in the zwitterion form, the other is not. [8] In the solid state, H 4 EDTA is a zwitterion with two protons having been transferred from carboxylic acid groups to the nitrogen atoms. [9] In psilocybin, the proton on the dimethyl amino group is labile and may jump to the phosphate group to form a compound which is not a zwitterion.
Polyethylene glycol. PEGylation (or pegylation) is the process of both covalent and non-covalent attachment or amalgamation of polyethylene glycol (PEG, in pharmacy called macrogol) polymer chains to molecules and macrostructures, such as a drug, therapeutic protein or vesicle, which is then described as PEGylated.