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Phytomenadione, also known as vitamin K 1 or phylloquinone, is a vitamin found in food and used as a dietary supplement. [6] [7] It is on the World Health Organization's List of Essential Medicines. [8] It is used to treat certain bleeding disorders, [7] including warfarin overdose, vitamin K deficiency, and obstructive jaundice. [7]
The compound is variously known as vitamin K 3 [7] and provitamin K 3. [8] Proponents of the latter name generally argue that the compound is not a real vitamin due to its artificial status (prior to its identification as a circulating intermediate) and its lack of a 3-methyl side chain preventing it from exerting all the functions (specifically, it cannot act as a cofactor for GGCX in vitro ...
Half the dogs received bedinvetmab and half the dogs received a sterile saline injection every 28 days for a total of three doses. [5] Before treatment and on various days throughout the study, owners used the Canine Brief Pain Inventory (CBPI) assessment tool to measure the severity of the dog's pain and the degree to which the pain interfered ...
Prednisolone is used in the treatment of inflammatory and allergic conditions in cats, dogs, horses, small mammals such as ferrets, birds, and reptiles. [ 57 ] [ 58 ] Its usage in treating inflammation, immune-mediated disease, Addison's disease , and neoplasia is often considered off-label use.
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
Masitinib is approved for the treatment of unresectable grade 2 and 3 (or high-grade) mastocytomas with c-KIT mutation. Side effects are primarily vomiting, diarrhea, neutropenia, anemia, and proteinuria, but most are mild. Median survival increased from 75 to 118 days in a study of dogs with grade 2 and 3 tumors without metastases, and to 253 ...
Beneficial side effects are less common; some examples, in many cases of side-effects that ultimately gained regulatory approval as intended effects, are: Bevacizumab , used to slow the growth of blood vessels, has been used against dry age-related macular degeneration, as well as macular edema from diseases such as diabetic retinopathy and ...
Thrombolysis, also called fibrinolytic therapy, is the breakdown of blood clots formed in blood vessels, using medication.It is used in ST elevation myocardial infarction, stroke, and in cases of severe venous thromboembolism (massive pulmonary embolism or extensive deep vein thrombosis).