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With the 2001 Thermo Cardiosystems merger, Thoratec acquired the HeartMate Left Ventricular Assist System, an implanted VAD for end-stage heart patients. A landmark three-year study of 129 patients at 22 major medical centers, called REMATCH (Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure) and published in November 2001, found that the HeartMate VE ...
The HeartMate II pivotal trial began in 2005 and included the evaluation of HeartMate II for two indications: Bridge to transplantation (BTT) and destination therapy (DT), or long-term, permanent support. Thoratec Corp. announced that this was the first time the FDA had approved a clinical trial to include both indications in one protocol.
O. H. "Bud" Frazier is a heart surgeon and director of cardiovascular surgery research at the Texas Heart Institute (THI), best known for his work in mechanical circulatory support (MCS) of failing hearts using left ventricular assist devices (LVAD) and total artificial hearts (TAH).
[2] [3] In addition, destination therapy may in some cases turn out to remedy the condition that excluded transplantation [4] Estimates place the population in the United States that may benefit from destination therapy at 50,000 – 100,000 patients per year. The addressable population outside of the US is thought be similar in size.
User's guide for a Dulcitone keyboard. A user guide, also commonly known as a user manual, is intended to assist users in using a particular product, service or application. It is usually written by a technician, product developer, or a company's customer service staff. Most user guides contain both a written guide and associated images.
2007 Toyota Yaris hatchback owner's manual 1919 Ford Motor Company car and truck operating manual. An owner's manual (also called an instruction manual or a user guide) is an instructional book or booklet that is supplied with almost all technologically advanced consumer products such as vehicles, home appliances and computer peripherals.
The first edition of The Merck Manual was published in 1899 by Merck & Co., Inc. for physicians and pharmacists and was titled Merck's Manual of the Materia Medica. [6] [7] The 192 page book which sold for US $1.00, was divided into three sections, Part I ("Materia Medica") was an alphabetical listing of all known compounds thought to be of therapeutic value with uses and doses; Part II ...
This manual supersedes FM 3-0, dated 6 October 2017. James C. McConville: INACTIVE: ADP 3–0 (FM 3–0) ADP 3–0, Unified Land Operations: 10 October 2011 [13] This manual supersedes FM 3–0, dated 27 February 2008 and Change 1, dated 22 February 2011. Raymond T. Odierno: INACTIVE: FM 3–0 (incl. C1) FM 3–0, Operations (with included ...