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RNFL asymmetry has been proposed as a strong indicator of optic neuritis, [7] [8] with one small study proposing that asymmetry of 5–6μm was "a robust structural threshold for identifying the presence of a unilateral optic nerve lesion in MS." [9] Optic neuritis is often associated with multiple sclerosis, and RNFL data may indicate the pace ...
The optic nerve contains axons of nerve cells that emerge from the retina, leave the eye at the optic disc, and go to the visual cortex where input from the eye is processed into vision. There are 1.2 million optic nerve fibers that derive from the retinal ganglion cells of the inner retina. [2] Damage to the optic nerve can have different causes:
Visual field-tubular vision Visual field-central scotoma. Lesions involving the whole optic nerve cause complete blindness on the affected side, that means damage at the right optic nerve causes complete loss of vision in the right eye. [3] Optic neuritis involving external fibers of the optic nerve causes tunnel vision. [4]
Major symptoms are sudden loss of vision (partial or complete), sudden blurred or "foggy" vision, and; pain on movement of the affected eye. [4] [5] [2]Many patients with optic neuritis may lose some of their color vision in the affected eye (especially red), with colors appearing subtly washed out compared to the other eye.
To form the right visual field, temporal retinal fibers from the left eye and nasal retinal fibers from the right eye form the left optic tract, and to form the left visual field, temporal retinal fibers from the right eye and nasal retinal fibers from the left eye form the right optic tract. [3]
The inferonasal retina are related to the anterior portion of the optic chiasm whereas superonasal retinal fibers are related to the posterior portion of the optic chiasm. The partial crossing over of optic nerve fibres at the optic chiasm allows the visual cortex to receive the same hemispheric visual field from both eyes.
A lesion in the optic nerve of one eye causes partial or complete loss of vision in the same eye, with an intact field of vision in other eye. A lesion at the proximal part of optic nerve of one eye cause, central field defect in one eye and temporal half-field defect in the other eye (not shown in the figure). [20]
The ganglion cell axons form the optic nerve after they leave the eye. The optic disc represents the beginning of the optic nerve and is the point where the axons of retinal ganglion cells come together. The optic disc in a normal human eye carries 1–1.2 million afferent nerve fibers from the eye toward the brain.
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