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  2. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Some patients request to be switched to a different narcotic due to stigma associated with a particular drug (e.g. a patient refusing methadone due to its association with opioid addiction treatment). [4] Equianalgesic charts are also used when calculating an equivalent dosage of the same drug, but with a different route of administration.

  3. Buprenorphine/naloxone - Wikipedia

    en.wikipedia.org/wiki/Buprenorphine/naloxone

    Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. [3] It is used to treat opioid use disorder, and reduces the mortality of opioid use disorder by 50% (by reducing the risk of overdose on full-agonist opioids such as heroin or fentanyl).

  4. Buprenorphine - Wikipedia

    en.wikipedia.org/wiki/Buprenorphine

    In the European Union, Subutex and Suboxone, buprenorphine's high-dose sublingual tablet preparations, were approved for opioid use disorder treatment in September 2006. [106] In the Netherlands, buprenorphine is a list II drug of the Opium Law, though special rules and guidelines apply to its prescription and dispensation. In France ...

  5. Neonatal withdrawal - Wikipedia

    en.wikipedia.org/wiki/Neonatal_withdrawal

    There are pre- and post-natal exposure risk of neurobehavioral disorders. The exposure during pregnancy can alter the newborn infants' short and long term adverse effects. This can include low birth weight, reduced head circumference, cognitive deficits, emotional dysregulation, high impulsiveness, and higher risk to develop a substance ...

  6. Indiana toddler dies after ingesting pill used to treat ... - AOL

    www.aol.com/news/indiana-toddler-dies-ingesting...

    An 18-month-old Indiana toddler tragically died days after ingesting a pill used to treat opioid addiction that she found in a thrift store backpack, according to family and officials.

  7. Naloxone - Wikipedia

    en.wikipedia.org/wiki/Naloxone

    A single administration of naloxone at a relatively high dose of 2 mg by intravenous injection has been found to produce brain MOR blockade of 80% at 5 minutes, 47% at 2 hours, 44% at 4 hours, and 8% at 8 hours. [72] A low dose (2 μg/kg) produced brain MOR blockade of 42% at 5 minutes, 36% at 2 hours, 33% at 4 hours, and 10% at 8 hours. [72]

  8. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...

  9. Opioid use disorder - Wikipedia

    en.wikipedia.org/wiki/Opioid_use_disorder

    [140] [141] It is not as widely used as buprenorphine or methadone for OUD due to low rates of patient acceptance, non-adherence due to daily dosing, and difficulty achieving abstinence from opioids before beginning treatment. Additionally, dosing naltrexone after recent opioid use can lead to precipitated withdrawal.