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Rare. Transient neonatal myasthenia gravis, i.e., TNMG (also termed neonatal myasthenia gravis [1]), and its more severe form, fetal acetylcholine receptor inactivation syndrome (i.e., FARIS), is one of the various types of myasthenia gravis (i.e., MG). [2] MG is an autoimmune disease in which individuals form antibodies that circulate in their ...
Myasthenia gravis is an autoimmune disease of the neuromuscular junction which results from antibodies that block or destroy nicotinic acetylcholine receptors (AChR) at the junction between the nerve and muscle. [6][7][1] This prevents nerve impulses from triggering muscle contractions. [1]
A tensilon test, also called an edrophonium test, is a pharmacological test used for the diagnosis of certain neural diseases, especially myasthenia gravis. [1] It is also used to distinguish a myasthenic crisis from a cholinergic crisis in individuals undergoing treatment for myasthenia gravis. The test has fallen out of use due to suboptimal ...
Simpson test. Purpose. determine ocular myasthenia gravis. Simpson test is a clinical test used in neurology to determine ocular myasthenia gravis. [1] It was first described by the Scottish neurologist John Alexander Simpson. [2]
Myasthenia gravis is caused by autoantibodies to the postsynaptic acetylcholine receptors. Lambert–Eaton myasthenic syndrome (LEMS) is a rare autoimmune disorder characterized by muscle weakness of the limbs. It is also known as myasthenic syndrome, Eaton–Lambert syndrome, and when related to cancer, carcinomatous myopathy.
In practice, the edrophonium test has been replaced by testing for autoantibodies, including acetylcholine receptor (AchR) autoantibodies and muscle specific tyrosine kinase (MuSK) autoantibodies. [1] [2] Lambert-Eaton myasthenic syndrome (LEMS), is similar to myasthenia gravis in that it is an autoimmune disease.
Bienfang's test is a clinical test used in the diagnosis of ocular myasthenia gravis. It is used in conjunction with other examination techniques such as Cogan's lid twitch test [1] or enhancement of blepharoptosis from prolonged upward gaze. [2][3] It is a simple, quick, and non-invasive test for ocular myasthenia gravis that can be performed ...
Repetitive nerve stimulation is used to diagnose neuromuscular junction (NMJ) disorders, the most common of which is myasthenia gravis. A decremental response (a smaller and smaller muscle response with each repetitive stimulus) is abnormal and indicates NMJ dysfunction. This can be further confirmed if the response normalizes after ...
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