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Malignancy (from Latin male 'badly' and -gnus 'born') is the tendency of a medical condition to become progressively worse; the term is most familiar as a characterization of cancer. A malignant tumor contrasts with a non-cancerous benign tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues ...
All tumor cells show the six hallmarks of cancer. These characteristics are required to produce a malignant tumor. They include: [29] Cell growth and division absent the proper signals; Continuous growth and division even given contrary signals; Avoidance of programmed cell death; Limitless number of cell divisions; Promoting blood vessel ...
Eventually, the tumor burden increasingly interferes with normal biochemical functions carried out by the host's organs, and death ultimately ensues. Carcinoma is but one form of cancer—one composed of cells that have developed the cytological appearance, histological architecture, or molecular characteristics of epithelial cells.
Tumor is also not synonymous with cancer. While cancer is by definition malignant, a tumor can be benign, precancerous, or malignant. [citation needed] The terms mass and nodule are often used synonymously with tumor. Generally speaking, however, the term tumor is used generically, without reference to the physical size of the lesion. [3]
Adenocarcinoma is the malignant counterpart to adenoma, which is the benign form of such tumors. Sometimes adenomas transform into adenocarcinomas, but most do not. Well- differentiated adenocarcinomas tend to resemble the glandular tissue that they are derived from, while poorly differentiated adenocarcinomas may not.
It is what dictates whether the tumor is benign or malignant, and is the property which enables their dissemination around the body. The cancer cells have to undergo a multitude of changes in order for them to acquire the ability to metastasize, in a multistep process that starts with local invasion of the cells into the surrounding tissues.
A: One of more than 125 types of primary brain and other central nervous system tumors (including both benign and malignant tumors, but not including metastatic lesions) are diagnosed in about ...
A malignant tumor is defined by its capacity to initiate a biological phenomenon known as the metastatic cascade, a complex multi-stage process in which cell invasion precedes further cancer progression and the formation of metastases in distant organs and tissues. Massive metastatic lesions lead to the development of organ failure.
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