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Schilder disease or diffuse myelinoclastic sclerosis: is a rare disease that presents clinically as a pseudotumoural demyelinating lesion; and is more common in children. [56] [57] Solitary sclerosis: This variant was proposed (2012) by Mayo Clinic researchers. [58] though it was also reported by other groups more or less at the same time.
Normally a tumefactive demyelinating lesion appears together with smaller disseminated lesions. Hence the name "tumefactive multiple sclerosis". When the demyelinating lesion appears alone it has been termed "solitary sclerosis" [citation needed] This variant was first proposed (2012) by Mayo Clinic researches.
The specific symptoms depend on the locations of the lesions within the nervous system, and may include focal loss of sensitivity or changes in sensation in the limbs, such as feeling tingling, pins and needles, or numbness; limb motor weakness/pain, blurred vision, [29] pronounced reflexes, muscle spasms, difficulty with ambulation (walking ...
There are many cortical and subcortical structures implicated in urination [54] and MS lesions in various central nervous system structures can cause these kinds of symptoms. Treatment objectives are the alleviation of symptoms of urinary dysfunction, treatment of urinary infections, reduction of complicating factors and the preservation of ...
Multiple sclerosis is typically diagnosed based on the presenting signs and symptoms, in combination with supporting medical imaging and laboratory testing. [4] It can be difficult to confirm, especially early on, since the signs and symptoms may be similar to those of other medical problems.
Nearly 2.3 million people are estimated to be living with multiple sclerosis around the world, but when Montel Williams received his official diagnosis back in 1999, not much was known about the ...
In any case, understanding lesion patterns can provide information about differences in disease between individuals and enable doctors to make more effective treatment decisions. [ citation needed ] According to one of the researchers involved in the original research, "Two patterns (I and II) showed close similarities to T-cell-mediated or T ...
When joint pain is severe and doesn’t respond to the treatments described above, surgery may be necessary. The types of surgery that may be used include : Partial or total joint replacement ...