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  2. This Chronic Skin Condition Is A Common Cause Of Dark ... - AOL

    www.aol.com/lifestyle/chronic-skin-condition...

    In short, melasma is a chronic skin condition that appears as darkened areas on the face due to an overproduction of melanin, says Gina Charles, MO, a family physician specializing in skincare. It ...

  3. Hyperpigmentation - Wikipedia

    en.wikipedia.org/wiki/Hyperpigmentation

    There are a wide range of depigmenting treatments used for hyperpigmentation conditions, and responses to most are variable. [11]Most often treatment of hyperpigmentation caused by melanin overproduction (such as melasma, acne scarring, liver spots) includes the use of topical depigmenting agents, which vary in their efficacy and safety, as well as in prescription rules.

  4. Acanthosis nigricans - Wikipedia

    en.wikipedia.org/wiki/Acanthosis_nigricans

    Higher than normal insulin levels in the blood stream cause the growth of darkened skin over certain areas of the body. No skin treatment will cure it, but acanthosis nigricans may lighten up and possibly disappear by treating the root cause, insulin resistance, but it can take months or years to do so. [ 11 ]

  5. Melasma - Wikipedia

    en.wikipedia.org/wiki/Melasma

    The exact cause of melasma is unknown. [6] Melasma is thought to be the stimulation of melanocytes (cells in the dermal layer, which transfer the pigment melanin to the keratinocytes of skin) when the skin is exposed to ultraviolet light from the sun. Small amounts of sun exposure can make melasma return to the skin after it has faded, which is ...

  6. Schamberg disease - Wikipedia

    en.wikipedia.org/wiki/Schamberg_disease

    Schamberg's disease is a skin disorder that causes a discoloration of the lower extremities. [4] It usually occurs in the lower extremities and rarely elsewhere. [4] This condition is caused by leaky blood vessels near the surface of the skin. [7] The cause of the leaky capillaries is usually not known. [7]

  7. I-cell - Wikipedia

    en.wikipedia.org/wiki/I-cell

    These inclusions disrupt cellular functions and cause symptoms like developmental delays, abnormal growth, coarse facial features, and enlarged organs. This mutation is inherited in an autosomal recessive manner, so both parents must be carriers of one copy of the mutated gene in order for kin to develop this condition.

  8. Pellagra - Wikipedia

    en.wikipedia.org/wiki/Pellagra

    Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B 3). [2] Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. [1] Areas of the skin exposed to friction and radiation are typically affected first. [1]

  9. List of skin conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_skin_conditions

    The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]

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