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Desmopressin (1-deamino-8-D-arginine vasopressin) is a synthetic form of the normal human hormone arginine vasopressin (the antidiuretic hormone, or ADH), a peptide containing nine amino acids. Compared to vasopressin, desmopressin's first amino acid has been deaminated , and the arginine at the eighth position is in the dextro rather than the ...
Nocturia is defined by the International Continence Society (ICS) as "the complaint that the individual has to wake at night one or more times for voiding (i.e., to urinate)". [1] The term is derived from Latin nox – "night", and Greek [τα] ούρα – "urine".
US drug regulators have banned using desmopressin nasal sprays for treating bedwetting since the oral form is considered safer. DDAVP is most efficient in children with nocturnal polyuria (nocturnal urine production greater than 130% of expected bladder capacity for age) and normal bladder reservoir function (maximum voided volume greater than ...
Nocturia is the need of frequent urination at night. [1] The most common cause of this condition for women and children is a urinary tract infection. The most common cause of urinary frequency in older men is an enlarged prostate. [2]
Untreated central diabetes insipidus patients usually exhibit polyuria, nocturia, and polydipsia as a result of the initial rise of serum sodium and osmolality. [5] Patients may also experience neurologic symptoms associated with the underlying illness, such as headaches and diplopia, depending on the exact origin of the central diabetes insipidus.
The hormone can be boosted by a synthetic version known as desmopressin, or DDAVP. [21] Desmopressin is approved by the United States Food & Drug Administration (FDA) for use in children 6 years and older with primary nocturnal enuresis and is available in both spray and tablet formulations.
Desmopressin can also be used; if the patient is able to concentrate urine following administration of desmopressin, then the cause of the diabetes insipidus is neurogenic diabetes insipidus; if no response occurs to desmopressin, then the cause is likely to be nephrogenic.
Prevalence increases with age. The prevalence of nocturia in older men is about 78%. Older men have a higher incidence of LUTS than older women. [25] Around one third of men will develop urinary tract (outflow) symptoms, of which the principal underlying cause is benign prostatic hyperplasia. [26]
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related to: desmopressin for nocturia in elderly mayo clinic- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
Working to be "the most powerful patient advocate in America" - Forbes