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Ion channels are located within the membrane of all excitable cells, [ 3] and of many intracellular organelles. They are often described as narrow, water-filled tunnels that allow only ions of a certain size and/or charge to pass through. This characteristic is called selective permeability.
The channelome, sometimes called the "ion channelome", is the complete set of ion channels and porins expressed in a biological tissue or organism. It is analogous to the genome , the metabolome (describing metabolites), the proteome (describing general protein expression), and the microbiome .
Voltage-gated ion channels have a crucial role in excitable cells such as neuronal and muscle tissues, allowing a rapid and co-ordinated depolarization in response to triggering voltage change. Found along the axon and at the synapse, voltage-gated ion channels directionally propagate electrical signals. Voltage-gated ion-channels are usually ...
Total Recall is a 1990 American science-fiction action film directed by Paul Verhoeven (pictured). Based on a 1966 short story by Philip K. Dick, the film stars Arnold Schwarzenegger, Rachel Ticotin, Sharon Stone, Ronny Cox, and Michael Ironside. It tells the story of Douglas Quaid (Schwarzenegger) and the shadow organization that tries to ...
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Acid-sensing ion channel. Alpha-3 beta-2 nicotinic receptor. Alpha-3 beta-4 nicotinic receptor. Alpha-4 beta-2 nicotinic receptor. Alpha-7 nicotinic receptor. Anion-conducting channelrhodopsin. ASIC5.
Gating (electrophysiology) An animated representation of the molecular structure of a simple ion channel. In electrophysiology, the term gating refers to the opening ( activation) or closing (by deactivation or inactivation) of ion channels. [ 1] This change in conformation is a response to changes in transmembrane voltage.
Voltage-gated sodium channels ( VGSCs ), also known as voltage-dependent sodium channels ( VDSCs ), are a group of voltage-gated ion channels found in the membrane of excitable cells ( e.g., muscle, glial cells, neurons, etc.) with a permeability to the sodium ion Na +. They are the main channels involved in action potential of excitable cells.