Search results
Results from the WOW.Com Content Network
Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix , a gel-like structure ...
Cell adhesion molecule. Cell adhesion molecules (CAMs) are a subset of cell surface proteins [1] that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. [2] In essence, CAMs help cells stick to each other and to their surroundings.
Cell-'Extra-Cellular Matrix' (ECM) adhesions also form mechanical and chemical linkages, but the connection occurs between cellular-matrix and the extra-cellular matrix through a plethora of adhesive proteins that form cohesive functional units. These focal adhesion plaques are highly dynamic in nature and undergo a maturation process through ...
The epithelial–mesenchymal transition (EMT) is a process by which epithelial cells lose their cell polarity and cell–cell adhesion, and gain migratory and invasive properties to become mesenchymal stem cells; these are multipotent stromal cells that can differentiate into a variety of cell types. EMT is essential for numerous developmental ...
In this diagram, the interface between neighboring cells or the basolateral membrane is depicted as "sheets"; the space between these sheets being the extracellular environment and the location of adhesion protein interaction. Stable cell-cell interactions are required for cell adhesion within a tissue and controlling the shape and function of ...
Substrate adhesion molecules (SAMs) are proteins that attach cells to specific compounds in the extracellular matrix (a process known as cell adhesion). [1] Some of the amino acids in the SAM bind to components of the extracellular matrix, while others bind to integrins on the surface of the cell. Integrin molecules are composed of two chains ...
As the cell progresses along its chosen path, a given focal adhesion moves closer and closer to the trailing edge of the cell. At the trailing edge of the cell the focal adhesion must be dissolved. The mechanism of this is poorly understood and is probably instigated by a variety of different methods depending on the circumstances of the cell.
Cell adhesion can occur in two ways; by focal adhesions, connecting the ECM to actin filaments of the cell, and hemidesmosomes, connecting the ECM to intermediate filaments such as keratin. This cell-to-ECM adhesion is regulated by specific cell-surface cellular adhesion molecules (CAM) known as integrins. Integrins are cell-surface proteins ...