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Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [ 1 ] Recently, a third form of liver failure known as acute-on-chronic liver failure ( ACLF ) is increasingly being recognized.
Acute liver failure is the appearance of severe complications rapidly after the first signs (such as jaundice) of liver disease, and indicates that the liver has sustained severe damage (loss of function of 80–90% of liver cells).
Alcoholic liver disease is a hepatic manifestation of alcohol overconsumption, including fatty liver disease, alcoholic hepatitis, and cirrhosis. Analogous terms such as "drug-induced" or "toxic" liver disease are also used to refer to disorders caused by various drugs.
Nonalcoholic fatty liver disease is a common but often overlooked condition affecting 1 in 4 Americans. It results from fat buildup in the liver, which can lead to inflammation, scarring, and ...
Rates of nonalcoholic fatty liver disease have been soaring over the past three decades, research finds. ... People who do have symptoms may feel fatigued or discomfort in the upper right side of ...
Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, chronic liver failure or chronic hepatic failure and end-stage liver disease, is a condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue and regenerative nodules as a result of chronic liver disease.
Hepatic encephalopathy (HE) is an altered level of consciousness as a result of liver failure. [2] Its onset may be gradual or sudden. [2] Other symptoms may include movement problems, changes in mood, or changes in personality. [2]
Human liver transplants were first performed by Thomas Starzl in the United States and Roy Calne in Cambridge, England in 1963 and 1967, respectively. After resection of left lobe liver tumor. Liver transplantation is the only option for those with irreversible liver failure.
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