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Alopecia totalis is the loss of all hair on the head and face.Its causes are unclear, but believed to be autoimmune.Research suggests there may be a genetic component linked to developing alopecia totalis; the presence of DRB1*0401 and DQB1*0301, both of which are human leukocyte antigens (HLA), were found to be associated with long-standing alopecia totalis.
It is important to note that treatment response to hair loss may be unpredictable and variable depending on the cause. 8.5% of patients with alopecia totalis may achieve complete recovery. [2] Certain conditions such as tinea capitis and trichotillomania usually respond once the infection or hair pulling behaviors are stopped. [ 3 ]
Treatment depends on the type of alopecia and the extent of the hair loss. “If it’s alopecia areata, we do tell patients that actually in most (cases) it will grow back,” says Dr Mehta.
The US Food and Drug Administration (FDA) approved ritlecitinib based on evidence from a clinical trial of 718 participants with severe alopecia areata. [11] The efficacy and safety of ritlecitinib were evaluated in a randomized, double-blind, placebo controlled trial in 718 participants twelve years of age and older with alopecia areata with ≥50% scalp hair loss, including alopecia totalis ...
Alopecia totalis. This type of alopecia areata causes hair loss on all or nearly the entire scalp. Alopecia universalis. In this rare type of alopecia areata, hair on the scalp, face and the rest ...
Alopecia areata, on the other hand, is caused by an autoimmune disease. It happens when your immune system mistakenly attacks hair follicles. Stress is the main driver of telogen effluvium.
Androgenic alopecia also occurs in women, and more often presents as diffuse thinning without hairline recession. Like its male counterpart, the condition rarely leads to total hair loss . Treatment options are similar to those for men, although topical or systemic estrogen is used more often.
A 2021 review found that oral minoxidil is a “successful and well-tolerated alternative for patients with hair ... minoxidil were effective treatments for male androgenetic alopecia, finasteride ...