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Lubiprostone, sold under the brand name Amitiza among others, is a medication used in the management of chronic idiopathic constipation, predominantly irritable bowel syndrome-associated constipation in women and opioid-induced constipation. The drug is owned by Mallinckrodt and is marketed by Takeda Pharmaceutical Company.
Plecanatide, sold under the brand name Trulance, is a medication for the treatment of chronic idiopathic constipation (CIC) [4] and irritable bowel syndrome with constipation. [5] It is available in India under the brand name Plectide (OQM Div, MSN Laboratories, India). Plecanatide is an agonist of guanylate cyclase-C.
Eluxadoline, sold under the brand names Viberzi and Truberzi, [3] is a medication taken by mouth for the treatment of diarrhea and abdominal pain in individuals with diarrhea-predominant irritable bowel syndrome (IBS-D). [4]
About Chronic Constipation (excluding constipation caused by organic diseases) According to MHLW epidemiology data, millions of people in Japan may live daily with the pain and discomfort of ...
They are used to treat and prevent constipation. Laxatives vary as to how they work and the side effects they may have. Certain stimulant , lubricant , and saline laxatives are used to evacuate the colon for rectal and bowel examinations, and may be supplemented by enemas under certain circumstances.
The company was founded by Ryuji Ueno and Sachiko Kuno in 1996. [1]In January 2006, the company received approval from the Food and Drug Administration for Amitiza. [2]In 2010, the company entered into arbitration with its partner, Takeda Pharmaceutical Company, claiming that sales of Amitiza floundered because of a half-hearted marketing effort by Takeda.
Constipation is the most common chronic gastrointestinal disorder in adults. Depending on the definition employed, it occurs in 2% to 20% of the population. [18] [58] It is more common in women, the elderly and children. [58] Specifically constipation with no known cause affects females more often affected than males. [59]
When Joe Biden and Donald Trump met on a debate stage in October 2020, the result was…something.. The Washington Post called it "the worst presidential debate in living memory." For media ...
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