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Pericytes and renal mesangial cells are some examples of modified myofibroblast-like cells. Myofibroblasts may interfere with the propagation of electrical signals [5] controlling heart rhythm, [6] leading to arrhythmia in both patients who have suffered a heart attack and in foetuses. Ursodiol is a promising drug for this condition. [7]
Parietal epithelial cell (PEC) Podocyte; Angioblast → Endothelial cell; Mesangial cell. Intraglomerular; Extraglomerular; Juxtaglomerular cell; Macula densa cell; Stromal cell → Interstitial cell → Telocytes; Kidney proximal tubule brush border cell; Kidney distal tubule cell; Connecting tubule cells; α-intercalated cell; β-intercalated ...
Pancreatic stellate cells (PaSCs) are classified as myofibroblast-like cells that are located in exocrine regions of the pancreas. [ 1 ] [ 2 ] PaSCs are mediated by paracrine and autocrine stimuli and share similarities with the hepatic stellate cell . [ 2 ]
The site of keratinocyte stem cells remains unknown but stem cells are likely to reside in the basal layer of the epidermis and below the bulge area of hair follicles. The fibroblast involved in scarring and contraction is the myofibroblast, [30] which is a specialized contractile fibroblast. [31] These cells express α-smooth muscle actin (α ...
The inner layer is mainly composed of two cell types, specialized macrophages (macrophage-like synovial cells) and fibroblast-like synoviocytes, which are important in maintaining the internal joint homeostasis. These cells represent the main source of hyaluronic acid and also other glycoproteins, major components of the synovial fluid. [1] [2]
Unlike the epithelial cells lining the body structures, fibroblasts do not form flat monolayers and are not restricted by a polarizing attachment to a basal lamina on one side, although they may contribute to basal lamina components in some situations (e.g. subepithelial myofibroblasts in intestine may secrete the α-2 chain-carrying component ...
Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, [1] forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall. It is a thin layer of simple, or single-layered, squamous cells called endothelial cells. Endothelial cells in direct contact with blood are ...
Myoblasts (cells with a single nucleus, represented in violet) fusing together to form muscle fibers (multinucleated muscle cells) during myogenesis Myogenesis is the formation of skeletal muscular tissue , particularly during embryonic development .