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Galactoside acetyltransferase (also known as Galactoside O-acetyltransferase, thiogalactoside transacetylase, β-galactoside transacetylase and GAT) is an enzyme that transfers an acetyl group from acetyl-CoA to β-galactosides, glucosides and lactosides. It is coded for by the lacA gene of the lac operon in E. coli. [1]
The lactose operon (lac operon) is an operon required for the transport and metabolism of lactose in E. coli and many other enteric bacteria.Although glucose is the preferred carbon source for most enteric bacteria, the lac operon allows for the effective digestion of lactose when glucose is not available through the activity of β-galactosidase. [1]
Each unit of β-galactosidase consists of five domains; domain 1 is a jelly-roll type β-barrel, domain 2 and 4 are fibronectin type III-like barrels, domain 5 a novel β-sandwich, while the central domain 3 is a distorted TIM-type barrel, lacking the fifth helix with a distortion in the sixth strand. [8] The third domain contains the active ...
E. coli galactose-1-phosphate uridyltransferase. A deficiency of the human isoform of this transferase causes of galactosemia. Transferase deficiencies are at the root of many common illnesses. The most common result of a transferase deficiency is a buildup of a cellular product.
As the Trump Administration has pursued its goal of reducing government spending, it seems to be taking the same approach as big cats do when pursuing prey: move fast and take down the most ...
Galactoside permease is a protein coded by the lacY gene of the lac operon, and is found bound to the membrane of a cell for the purpose of binding galactoside molecules that have been solubilized. The protein is part of a system whose main function is to catalyze the accumulation and transport of lactose and other beta-galactosides across the ...
Earlier this month, broccoli was recalled from Walmart due to possible listeria contamination. On January 27, the U.S. Food and Drug Administration (FDA) updated the recall classification to Class ...
Nearly two years later, Ceonzo and her husband Joe got their answer. “He was about 3 when autism first came into our world,” she said. Unable to speak, read, or write, Joey was diagnosed with ...