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Methylene blue has been used as a placebo; physicians would tell their patients to expect their urine to change color and view this as a sign that their condition had improved. [32] This same side effect makes methylene blue difficult to use in traditional placebo-controlled clinical studies, including those testing for its efficacy as a treatment.
They inhibit release of thyroid hormones by the thyroid gland.The most studied drug in this class is lithium, which inhibits thyroid hormone secretion by inhibiting iodotyrosine coupling, thyroidal iodide uptake, and alteration in structure of thyroglobulin, [10] a protein which acts as a substrate for the synthesis of thyroid hormones and storage of inactive forms of T3, T4 and iodine within ...
The synthetic dye methylene blue, containing the structure, was described in 1876. Many water-soluble phenothiazine derivatives, such as methylene blue, methylene green, thionine, and others, can be electropolymerized into conductive polymers used as electrocatalysts for NADH oxidation in enzymatic biosensors and biofuel cells. [10] [11] [12]
New methylene blue (also NMB) [clarify] is an organic compound of the thiazine class of heterocycles. It is used as a stain and as an antimicrobial agent. It is classified as an azine dye, and the chromophore is a cation, the anion is often unspecified.
Liothyronine may be used when there is an impaired conversion of T 4 to T 3 in peripheral tissues. [2] The dose of liothyronine for hypothyroidism is a lower amount than levothyroxine due it being a higher concentrated synthetic medication. [2] About 25 μg of liothyronine is equivalent to 100 μg of levothyroxine. [3]
The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated cholesterol levels), but was withdrawn due to cardiac side effects. [ citation needed ] Once weekly thyroxine (OWT) preparations are also available for clinical use.
Thyroid medication is safe in pregnancy. [3] Although an adequate amount of dietary iodine is important, too much may worsen specific forms of hypothyroidism. [3] Worldwide about one billion people are estimated to be iodine-deficient; however, it is unknown how often this results in hypothyroidism. [11]
Methyl blue is a chemical compound with the molecular formula C 37 H 27 N 3 Na 2 O 9 S 3.It is used as a stain in histology, [1] and stains collagen blue in tissue sections. It can be used in some differential staining techniques such as Mallory's trichrome stain and Gömöri trichrome stain, and can be used to mediate electron transfer in microbial fuel cells.
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