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Granuloma; Picture of a granuloma (without necrosis) as seen through a microscope on a glass slide: The tissue on the slide is stained with two standard dyes (hematoxylin: blue, eosin: pink) to make it visible. The granuloma in this picture was found in a lymph node of a patient with a Mycobacterium avium infection. Specialty: Pathology
In this population, a biopsy of the gastrocnemius muscle is a useful tool in correctly diagnosing the person. The presence of a noncaseating epithelioid granuloma in a gastrocnemius specimen is definitive evidence of sarcoidosis, as other tuberculoid and fungal diseases extremely rarely present histologically in this muscle. [105]
Caseous necrosis in the kidney. In caseous necrosis no histological architecture is preserved (unlike with coagulative necrosis). [5] [6] On microscopic examination with H&E staining, the area is acellular, characterised by amorphous, roughly granular eosinophilic debris of now dead cells, [6] also containing interspearsed haematoxyphilic remnants of cell nucleus contents. [5]
They may appear as either non-caseating or solidly caseating lesions. [20] Initially, tuberculomas appear hypodense on computed tomography (CT) scans with significant surrounding edema. [ 23 ] [ 3 ] The "target sign" is pathognomonic for tuberculoma on CT, with a nodular ring-enhancing mass and central calcification.
Right image: MRI brain with contrast showing near resolution of enhancement after treatment. The diagnosis of neurosarcoidosis often is difficult. Definitive diagnosis can only be made by biopsy (surgically removing a tissue sample). Because of the risks associated with brain biopsies, they are avoided as much as possible.
Arachnoid granulations (also arachnoid villi, and Pacchionian granulations or bodies) are small outpouchings of the arachnoid mater and subarachnoid space into the dural venous sinuses of the brain. The granulations are thought to mediate the draining of cerebrospinal fluid (CSF) from the subarachnoid space into the venous system. [1]
Via brain scans, Llibre-Guerra and his team observed that while Whitney had high levels of amyloid protein in his brain, he only had a localized concentration of the protein tau.
Lymphomatoid means lymphoma-like and granulomatosis denotes the microscopic characteristic of the presence of granulomas with polymorphic lymphoid infiltrates and focal necrosis within it. LG most commonly affects middle aged people, [2] but has occasionally been observed in young people. [3] Males are found to be affected twice as often as ...