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For those who after weight loss still are anovulatory or for anovulatory lean women, ovulation induction to reverse the anovulation is the principal treatment used to help infertility in PCOS. Letrozole and Clomiphene citrate are the first-line treatment in subfertile anovulatory patients with PCOS. [12]
There is some evidence that letrozole can improve the rate of live births and the rate of pregnancy rate for people who experience anovulatory PCOS, and this treatment may be more effective than SERMs. [63] There is high quality evidence that the rate of people developing ovarian hyperstimulation syndrome is similar between SERMs and letrozole ...
Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom, and not the underlying cause of the disorder.
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Finally, many women with PCOS also struggle with their weight, which can increase risk of a slew of health conditions, including high cholesterol, high blood pressure, sleep apnea, stroke, and ...
The NSAI, letrozole is also used for ovulation induction in women with polycystic ovary syndrome (PCOS). [2] Generally, clomiphene citrate is used to induce ovulation, but for some women that treatment is unsuccessful or resistant occurs.
70% of women affected by PCOS remain undiagnosed worldwide. Why? Weight and gender bias play a crucial role.
Letrozole, sold under the brand name Femara among others, is an aromatase inhibitor medication that is used in the treatment of breast cancer. [ 1 ] It was patented in 1986 and approved for medical use in 1996. [ 4 ]
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