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  2. Receptor (biochemistry) - Wikipedia

    en.wikipedia.org/wiki/Receptor_(biochemistry)

    Receptors of a particular type are linked to specific cellular biochemical pathways that correspond to the signal. While numerous receptors are found in most cells, each receptor will only bind with ligands of a particular structure. This has been analogously compared to how locks will only accept specifically shaped keys. When a ligand binds ...

  3. Cell signaling - Wikipedia

    en.wikipedia.org/wiki/Cell_signaling

    Enzyme-linked receptors (or catalytic receptors) are transmembrane receptors that, upon activation by an extracellular ligand, causes enzymatic activity on the intracellular side. [33] Hence a catalytic receptor is an integral membrane protein possessing both enzymatic, catalytic, and receptor functions. [34]

  4. Upstream and downstream (transduction) - Wikipedia

    en.wikipedia.org/wiki/Upstream_and_downstream...

    The type II receptors phosphorylate the type I receptors; the type I receptors are then enabled to phosphorylate cytoplasmic R-Smads, which then act as transcriptional regulators. The upstream signaling pathway is triggered by the binding of a signaling molecule, a ligand, to a receiving molecule, a receptor. Receptors and ligands exist in many ...

  5. Cooperative binding - Wikipedia

    en.wikipedia.org/wiki/Cooperative_binding

    The first description of cooperative binding to a multi-site protein was developed by A.V. Hill. [4] Drawing on observations of oxygen binding to hemoglobin and the idea that cooperativity arose from the aggregation of hemoglobin molecules, each one binding one oxygen molecule, Hill suggested a phenomenological equation that has since been named after him:

  6. Cell biology - Wikipedia

    en.wikipedia.org/wiki/Cell_biology

    Centrioles: Function to produce spindle fibers which are used to separate chromosomes during cell division. Eukaryotic cells may also be composed of the following molecular components: Chromatin: This makes up chromosomes and is a mixture of DNA with various proteins. Cilia: They help to propel substances and can also be used for sensory ...

  7. Cell surface receptor - Wikipedia

    en.wikipedia.org/wiki/Cell_surface_receptor

    Membrane receptors are mainly divided by structure and function into 3 classes: The ion channel linked receptor; The enzyme-linked receptor; and The G protein-coupled receptor. Ion channel linked receptors have ion channels for anions and cations, and constitute a large family of multipass transmembrane proteins.

  8. Fundamentals of Biochemistry - Wikipedia

    en.wikipedia.org/wiki/Fundamentals_of_Biochemistry

    Fundamentals of Biochemistry: Life at the Molecular Level is a biochemistry textbook written by Donald Voet, Judith G. Voet and Charlotte W. Pratt. [1] [2] Published by John Wiley & Sons, it is a common undergraduate biochemistry textbook. As of 2016, the book has been published in 5 editions. [3]

  9. Scaffold protein - Wikipedia

    en.wikipedia.org/wiki/Scaffold_protein

    This particular function is considered a scaffold's most basic function. Scaffolds assemble signaling components of a cascade into complexes. This assembly may be able to enhance signaling specificity by preventing unnecessary interactions between signaling proteins, and enhance signaling efficiency by increasing the proximity and effective concentration of components in the scaffold complex.

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